College of
Human
Medicine

Published Research

  • González-Reymúndez A, de Los Campos G, Gutiérrez L, Lunt SY, Vazquez AI. Prediction of years of life after diagnosis of breast cancer using omics and omic-by-treatment interactions. Eur J Hum Genet. 2017 Mar 8. doi: 10.1038/ejhg.2017.12. [Epub ahead of print] PubMed PMID: 28272536.Lutes LD, Damschroder LJ, Masheb R, Kim HM,
  • Gillon L, Holleman RG, Goodrich DE, Lowery JC, Janney C, Kirsh S, Richardson CR. Behavioral Treatment for Veterans with Obesity: 24-Month Weight Outcomes from the ASPIRE-VA Small Changes Randomized Trial. J Gen Intern Med. 2017 Mar 7. doi: 10.1007/s11606-017-3987-0. [Epub ahead of print] PubMed PMID: 28271430.Dunn AR,
  • Stout KA, Ozawa M, Lohr KM, Hoffman CA, Bernstein AI, Li Y, Wang M, Sgobio C, Sastry N, Cai H, Caudle WM, Miller GW. Synaptic vesicle glycoprotein 2C (SV2C) modulates dopamine release and is disrupted in Parkinson disease. Proc Natl Acad Sci U S A. 2017 Mar 14;114(11): E2253-E2262. doi:10.1073/pnas.1616892114. PubMed PMID: 28246328.
  • Parra-Cardona JR, Yeh HH, Anthony JC. Epidemiological research on parent-child conflict in the United States: subgroup variations by place of birth and ethnicity, 2002-2013. PeerJ. 2017 Jan 24;5: e2905. doi: 10.7717/peerj.2905. PubMed PMID: 28149684; PubMed Central PMCID: PMC5267568.
  • Brincks AM, Enders CK, Llabre MM, Bulotsky-Shearer RJ, Prado G, Feaster DJ. Centering Predictor Variables in Three-Level Contextual Models. Multivariate Behav Res. 2016 Dec 7:0. [Epub ahead of print] PubMed PMID: 27925836.
  • Cheng HG, Anthony JC. A new era for drinking? Epidemiological evidence on adolescent male-female differences in drinking incidence in the United States and Europe. Soc Psychiatry Psychiatr Epidemiol. 2017 Jan;52(1):117-126. doi: 10.1007/s00127-016-1318-0. PubMed PMID: 27915406; PubMed Central PMCID: PMC5233577.
  • Vsevolozhskaya OA, Anthony JC. Inter-relationships Linking Probability of Becoming a Case of Nicotine Dependence With Frequency of Tobacco Cigarette Smoking. Nicotine Tob Res. 2016 Dec;18(12):2278-2282. PubMed PMID: 27613940; PubMed Central PMCID: PMC5103934.
  • Kozlowski AJ, Fabian M, Lad D, Delgado A. Feasibility and safety of a powered exoskeleton for assisted walking for persons with multiple sclerosis: a single-group preliminary study. Arch Phys Med Rehabil. 2017 Mar 15. pii: S0003-9993(17)30144-2. doi: 10.1016/j.apmr.2017.02.010. [Epub ahead of print] PubMed PMID: 28315666.
  • Amin-Hanjani, S., Turan, T. N., Du, X., Pandey, D. K., Rose-Finnell, L., Richardson, D. et al. (2017). Higher Stroke Risk with Lower Blood Pressure in Hemodynamic Vertebrobasilar Disease: Analysis from the VERiTAS Study. J.Stroke Cerebrovasc.Dis., 26(2), 403-410. doi:S1052-3057(16)30375-5 [pii];10.1016/j.jstrokecerebrovasdis.2016.09.044 [doi]. Retrieved from PM:28029608
  • Bauer, M., Glenn, T., Monteith, S., Bauer, R., Whybrow, P. C., & Geddes, J. (2017). Ethical perspectives on recommending digital technology for patients with mental illness. Int.J.Bipolar.Disord., 5(1), 6. doi:10.1186/s40345-017-0073-9 [doi];10.1186/s40345-017-0073-9 [pii]. Retrieved from PM:28155206
  • Brincks, A. M., Enders, C. K., Llabre, M. M., Bulotsky-Shearer, R. J., Prado, G., & Feaster, D. J. (2016). Centering Predictor Variables in Three-Level Contextual Models. Multivariate.Behav.Res., 0. doi:10.1080/00273171.2016.1256753 [doi]. Retrieved from PM:27925836
  • Cheng, H. G., & Anthony, J. C. (2017). A new era for drinking? Epidemiological evidence on adolescent male-female differences in drinking incidence in the United States and Europe. Soc.Psychiatry Psychiatr.Epidemiol., 52(1), 117-126. doi:10.1007/s00127-016-1318-0 [doi];10.1007/s00127-016-1318-0 [pii]. Retrieved from PM:27915406
  • Cliburn, R. A., Dunn, A. R., Stout, K. A., Hoffman, C. A., Lohr, K. M., Bernstein, A. I. et al. (2016). Immunochemical localization of vesicular monoamine transporter 2 (VMAT2) in mouse brain. J.Chem.Neuroanat.. doi:S0891-0618(16)30095-3 [pii];10.1016/j.jchemneu.2016.11.003 [doi]. Retrieved from PM:27836486
  • Coles, A., Haveman-Gould, B., Farooq, M. U., Selke, K. J., & Gorelick, P. B. (2016). A Case of Complex PFO Leading to Ischemic Stroke: A Practical Clinical Pearl for Neurohospitalists. Neurohospitalist., 6(3), 114-117. doi:10.1177/1941874415588750 [doi];10.1177_1941874415588750 [pii]. Retrieved from PM:27366295
  • Combs, B., Hamel, C., & Kanaan, N. M. (2016). Pathological conformations involving the amino terminus of tau occur early in Alzheimer's disease and are differentially detected by monoclonal antibodies. Neurobiol.Dis., 94, 18-31. doi:S0969-9961(16)30119-X [pii];10.1016/j.nbd.2016.05.016 [doi]. Retrieved from PM:27260838
  • Counts, S. E., Ikonomovic, M. D., Mercado, N., Vega, I. E., & Mufson, E. J. (2017). Biomarkers for the Early Detection and Progression of Alzheimer's Disease. Neurotherapeutics., 14(1), 35-53. doi:10.1007/s13311-016-0481-z [doi];10.1007/s13311-016-0481-z [pii]. Retrieved from PM:27738903
  • Cox, K., Combs, B., Abdelmesih, B., Morfini, G., Brady, S. T., & Kanaan, N. M. (2016). Analysis of isoform-specific tau aggregates suggests a common toxic mechanism involving similar pathological conformations and axonal transport inhibition. Neurobiol.Aging, 47, 113-126. doi:S0197-4580(16)30152-X [pii];10.1016/j.neurobiolaging.2016.07.015 [doi]. Retrieved from PM:27574109
  • Farooq, M. U., & Gorelick, P. B. (2016). Neurology Case Studies: Cerebrovascular Disease. Neurol.Clin., 34(3), 467-482. doi:S0733-8619(16)30001-9 [pii];10.1016/j.ncl.2016.04.001 [doi]. Retrieved from PM:27445238
  • Farooq, M. U., Goshgarian, C., Min, J., & Gorelick, P. B. (2016). Pathophysiology and management of reperfusion injury and hyperperfusion syndrome after carotid endarterectomy and carotid artery stenting. Exp.Transl.Stroke Med., 8(1), 7. doi:10.1186/s13231-016-0021-2 [doi];21 [pii]. Retrieved from PM:27602202
  • Fischer, D. L., Gombash, S. E., Kemp, C. J., Manfredsson, F. P., Polinski, N. K., Duffy, M. F. et al. (2016). Viral Vector-Based Modeling of Neurodegenerative Disorders: Parkinson's Disease. Methods Mol.Biol., 1382, 367-382. doi:10.1007/978-1-4939-3271-9_26 [doi]. Retrieved from PM:26611600
  • Ghosh, A., Tyson, T., George, S., Hildebrandt, E. N., Steiner, J. A., Madaj, Z. et al. (2016). Mitochondrial pyruvate carrier regulates autophagy, inflammation, and neurodegeneration in experimental models of Parkinson's disease. Sci.Transl.Med., 8(368), 368ra174. doi:8/368/368ra174 [pii];10.1126/scitranslmed.aag2210 [doi]. Retrieved from PM:27928028
  • Gorelick, P. B., & Farooq, M. U. (2016). Cerebral Microbleeds, Cognition, and Therapeutic Implications. JAMA Neurol., 73(8), 908-910. doi:2526489 [pii];10.1001/jamaneurol.2016.1388 [doi]. Retrieved from PM:27271086
  • Grabinski, T., & Kanaan, N. M. (2016). Novel Non-phosphorylated Serine 9/21 GSK3beta/alpha Antibodies: Expanding the Tools for Studying GSK3 Regulation. Front Mol.Neurosci., 9, 123. doi:10.3389/fnmol.2016.00123 [doi]. Retrieved from PM:27909397
  • Hamano, T., Shirafuji, N., Makino, C., Yen, S. H., Kanaan, N. M., Ueno, A. et al. (2016). Pioglitazone prevents tau oligomerization. Biochem.Biophys.Res.Commun., 478(3), 1035-1042. doi:S0006-291X(16)31271-2 [pii];10.1016/j.bbrc.2016.08.016 [doi]. Retrieved from PM:27543203
  • Harlow, M. L., Maloney, N., Roland, J., Guillen Navarro, M. J., Easton, M. K., Kitchen-Goosen, S. M. et al. (2016). Lurbinectedin Inactivates the Ewing Sarcoma Oncoprotein EWS-FLI1 by Redistributing It within the Nucleus. Cancer Res., 76(22), 6657-6668. doi:0008-5472.CAN-16-0568 [pii];10.1158/0008-5472.CAN-16-0568 [doi]. Retrieved from PM:27697767
  • Iadecola, C., Yaffe, K., Biller, J., Bratzke, L. C., Faraci, F. M., Gorelick, P. B. et al. (2016). Impact of Hypertension on Cognitive Function: A Scientific Statement From the American Heart Association. Hypertension, 68(6), e67-e94. doi:HYP.0000000000000053 [pii];10.1161/HYP.0000000000000053 [doi]. Retrieved from PM:27977393
  • Imamura, K., Sahara, N., Kanaan, N. M., Tsukita, K., Kondo, T., Kutoku, Y. et al. (2016). Calcium dysregulation contributes to neurodegeneration in FTLD patient iPSC-derived neurons. Sci.Rep., 6, 34904. doi:srep34904 [pii];10.1038/srep34904 [doi]. Retrieved from PM:27721502
  • Iqbal, K., Tran, D. A., Li, A. X., Warden, C., Bai, A. Y., Singh, P. et al. (2016). High type I error and misrepresentations in search for transgenerational epigenetic inheritance: response to Guerrero-Bosagna. Genome Biol., 17(1), 154. doi:10.1186/s13059-016-0981-5 [doi];10.1186/s13059-016-0981-5 [pii]. Retrieved from PM:27411809
  • Kang, S. S., Zhang, Z., Liu, X., Manfredsson, F. P., He, L., Iuvone, P. M. et al. (2017). alpha-Synuclein binds and sequesters PIKE-L into Lewy bodies, triggering dopaminergic cell death via AMPK hyperactivation. Proc.Natl.Acad.Sci.U.S.A, 114(5), 1183-1188. doi:1618627114 [pii];10.1073/pnas.1618627114 [doi]. Retrieved from PM:28096359
  • Kelly, S. C., He, B., Perez, S. E., Ginsberg, S. D., Mufson, E. J., & Counts, S. E. (2017). Locus coeruleus cellular and molecular pathology during the progression of Alzheimer's disease. Acta Neuropathol.Commun., 5(1), 8. doi:10.1186/s40478-017-0411-2 [doi];10.1186/s40478-017-0411-2 [pii]. Retrieved from PM:28109312
  • Korczyn, A. D., & Gorelick, P. B. (2016). In Memoriam: Milton Alter, MD, PhD (1929-2016). JAMA Neurol., 73(12), 1504. doi:2592268 [pii];10.1001/jamaneurol.2016.4562 [doi]. Retrieved from PM:27942731
  • Koss, D. J., Jones, G., Cranston, A., Gardner, H., Kanaan, N. M., & Platt, B. (2016). Soluble pre-fibrillar tau and beta-amyloid species emerge in early human Alzheimer's disease and track disease progression and cognitive decline. Acta Neuropathol., 132(6), 875-895. doi:10.1007/s00401-016-1632-3 [doi];10.1007/s00401-016-1632-3 [pii]. Retrieved from PM:27770234
  • Lee, S. H., Kim, B. J., Han, M. K., Park, T. H., Lee, K. B., Lee, B. C. et al. (2016). Should we exclude acute stroke patients with previous intracerebral hemorrhage from receiving intravenous thrombolysis? Int.J.Stroke, 11(7), 783-790. doi:1747493016654289 [pii];10.1177/1747493016654289 [doi]. Retrieved from PM:27312681
  • Lees, K. R., & Khatri, P. (2016). Stroke Treatment Academic Industry Roundtable Recommendations for Individual Data Pooling Analyses in Stroke. Stroke, 47(8), 2154-2159. doi:STROKEAHA.116.012966 [pii];10.1161/STROKEAHA.116.012966 [doi]. Retrieved from PM:27406108
  • Linklater, E. S., Tovar, E. A., Essenburg, C. J., Turner, L., Madaj, Z., Winn, M. E. et al. (2016). Targeting MET and EGFR crosstalk signaling in triple-negative breast cancers. Oncotarget., 7(43), 69903-69915. doi:12065 [pii];10.18632/oncotarget.12065 [doi]. Retrieved from PM:27655711
  • Lohr, K. M., Chen, M., Hoffman, C. A., McDaniel, M. J., Stout, K. A., Dunn, A. R. et al. (2016). Vesicular Monoamine Transporter 2 (VMAT2) Level Regulates MPTP Vulnerability and Clearance of Excess Dopamine in Mouse Striatal Terminals. Toxicol.Sci., 153(1), 79-88. doi:kfw106 [pii];10.1093/toxsci/kfw106 [doi]. Retrieved from PM:27287315
  • Machiela, E., Dues, D. J., Senchuk, M. M., & Van Raamsdonk, J. M. (2016). Oxidative stress is increased in C. elegans models of Huntington's disease but does not contribute to polyglutamine toxicity phenotypes. Neurobiol.Dis., 96, 1-11. doi:S0969-9961(16)30202-9 [pii];10.1016/j.nbd.2016.08.008 [doi]. Retrieved from PM:27544481
  • Mercado, N. M., Collier, T. J., Freeman, T., & Steece-Collier, K. (2016). Repairing the Aged Parkinsonian Striatum: Lessons from the Lab and Clinic. J.Clin.Cell Immunol., 7(6). doi:10.4172/2155-9899.1000476 [doi]. Retrieved from PM:28111608
  • Mufson, E. J., Ikonomovic, M. D., Counts, S. E., Perez, S. E., Malek-Ahmadi, M., Scheff, S. W. et al. (2016). Molecular and cellular pathophysiology of preclinical Alzheimer's disease. Behav.Brain Res., 311, 54-69. doi:S0166-4328(16)30305-9 [pii];10.1016/j.bbr.2016.05.030 [doi]. Retrieved from PM:27185734
  • Mufson, E. J., Perez, S. E., Nadeem, M., Mahady, L., Kanaan, N. M., Abrahamson, E. E. et al. (2016). Progression of tau pathology within cholinergic nucleus basalis neurons in chronic traumatic encephalopathy: A chronic effects of neurotrauma consortium study. Brain Inj., 30(12), 1399-1413. doi:10.1080/02699052.2016.1219058 [doi]. Retrieved from PM:27834536
  • Osgood, C. L., Maloney, N., Kidd, C. G., Kitchen-Goosen, S., Segars, L., Gebregiorgis, M. et al. (2016). Identification of Mithramycin Analogues with Improved Targeting of the EWS-FLI1 Transcription Factor. Clin.Cancer Res., 22(16), 4105-4118. doi:1078-0432.CCR-15-2624 [pii];10.1158/1078-0432.CCR-15-2624 [doi]. Retrieved from PM:26979396
  • Parra-Cardona, J. R., Yeh, H. H., & Anthony, J. C. (2017). Epidemiological research on parent-child conflict in the United States: subgroup variations by place of birth and ethnicity, 2002-2013. PeerJ., 5 , e2905. doi:10.7717/peerj.2905 [doi];2905 [pii]. Retrieved from PM:28149684
  • Polinski, N. K., Manfredsson, F. P., Benskey, M. J., Fischer, D. L., Kemp, C. J., Steece-Collier, K. et al. (2016). Impact of age and vector construct on striatal and nigral transgene expression. Mol.Ther.Methods Clin.Dev., 3, 16082. doi:10.1038/mtm.2016.82 [doi]. Retrieved from PM:27933309
  • Smith, E. E., Saposnik, G., Biessels, G. J., Doubal, F. N., Fornage, M., Gorelick, P. B. et al. (2017). Prevention of Stroke in Patients With Silent Cerebrovascular Disease: A Scientific Statement for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke, 48(2), e44-e71. doi:STR.0000000000000116 [pii];10.1161/STR.0000000000000116 [doi]. Retrieved from PM:27980126
  • Tiernan, C. T., Combs, B., Cox, K., Morfini, G., Brady, S. T., Counts, S. E. et al. (2016). Pseudophosphorylation of tau at S422 enhances SDS-stable dimer formation and impairs both anterograde and retrograde fast axonal transport. Exp.Neurol., 283(Pt A), 318-329. doi:S0014-4886(16)30195-9 [pii];10.1016/j.expneurol.2016.06.030 [doi]. Retrieved from PM:27373205
  • Van Raamsdonk, J. M., Vega, I. E., & Brundin, P. (2017). Oxidative stress in neurodegenerative disease: causation or association? Oncotarget.. doi:14650 [pii];10.18632/oncotarget.14650 [doi]. Retrieved from PM:28099897
  • Vega, I. E., & Collier, T. J. (2016). Editorial: Unraveling Neuroprotective and Neurodegenerative Signals in Neurodegeneration. Front Neurosci., 10, 328. doi:10.3389/fnins.2016.00328 [doi]. Retrieved from PM:27468259
  • Vsevolozhskaya, O. A., & Anthony, J. C. (2016). Inter-relationships Linking Probability of Becoming a Case of Nicotine Dependence With Frequency of Tobacco Cigarette Smoking. Nicotine.Tob.Res., 18(12), 2278-2282. doi:ntw159 [pii];10.1093/ntr/ntw159 [doi]. Retrieved from PM:27613940