College of
Human
Medicine

Published Research

JUNE

  • Combs B, Kanaan NM. Exposure of the Amino Terminus of Tau Is a Pathological Event in Multiple Tauopathies. Am J Pathol. 2017 Jun;187(6):1222-1229. doi: 10.1016/j.ajpath.2017.01.019. Epub 2017 Apr 14. PubMed PMID: 28413156.
  • Bailey JM, Colón-Rodríguez A, Atchison WD. Evaluating a Gene-Environment Interaction in Amyotrophic Lateral Sclerosis: Methylmercury Exposure and Mutated SOD1. Curr Environ Health Rep. 2017 Jun;4(2):200-207. doi: 10.1007/s40572-017-0144-1. Review. PubMed PMID: 28397096.
  • Bhatwadekar AD, Beli E, Diao Y, Chen J, Luo Q, Alex A, Caballero S, Dominguez JM 2nd, Salazar TE, Busik JV, Segal MS, Grant MB. Conditional Deletion of Bmall Accentuates Microvascular and Macrovascular Injury. Am J Pathol. 2017 Jun;187(6):1426-1435. doi: 10.1016/j.ajpath.2017.02.014. Epub 2017 Apr 19. PubMed PMID: 28432873.
  • Brown JP, Lynch BS, Curry-Chisolm IM, Shafer TJ, Strickland JD. Assaying Spontaneous Network Activity and Cellular Viability Using Multi-well Microelectrode Arrays. Methods Mol Biol. 2017;1601:153-170. doi: 10.1007/978-1-4939-6960-9_13. PubMed PMID: 28470525.
  • Cather C, Hoeppner S, Pachas G, Pratt S, Achtyes E, Cieslak KM, Evins AE. Improved Depressive Symptoms in Adults with Schizophrenia During a Smoking Cessation Attempt with Varenicline and Behavioral Therapy. J Dual Diagn. 2017 Apr 17:0. doi: 10.1080/15504263.2017.1319585. [Epub ahead of print] PubMed PMID: 28414583.
  • Hamilton PJ, Burek DJ, Lombroso SI, Neve RL, Robison AJ, Nestler EJ, Heller EA. Cell-Type Specific Epigenetic Editing at the Fosb Gene Controls Susceptibility to Social Defeat Stress. Neuropsychopharmacology. 2017 May 2. doi:10.1038/npp.2017.88. [Epub ahead of print] PubMed PMID: 28462942.
  • Kady N, Yan Y, Salazar T, Wang Q, Chakravarthy H, Huang C, Beli E, Navitskaya S, Grant M, Busik J. Increase in acid sphingomyelinase level in human retinal endothelial cells and CD34(+) circulating angiogenic cells isolated from diabetic individuals is associated with dysfunctional retinal vasculature and vascular repair process in diabetes. J Clin Lipidol. 2017 May - Jun;11(3):694-703. doi: 10.1016/j.jacl.2017.03.007. Epub 2017 Mar 30. PubMed PMID: 28457994.
  • Liu B, Fang F, Pedersen NL, Tillander A, Ludvigsson JF, Ekbom A, Svenningsson P, Chen H, Wirdefeldt K. Vagotomy and Parkinson disease: A Swedish register-based matched-cohort study. Neurology. 2017 May 23;88(21):1996-2002. doi: 10.1212/WNL.0000000000003961. Epub 2017 Apr 26. PubMed PMID: 28446653.
  • Misek S, Chen J, Schroeder L, Rattanasinchai C, Sample A, Sarkaria JN, Gallo KA. EGFR Signals through a DOCK180-MLK3 Axis to Drive Glioblastoma Cell Invasion. Mol Cancer Res. 2017 May 9. pii: molcanres.0318.2016. doi: 10.1158/1541-7786.MCR-16-0318. [Epub ahead of print] PubMed PMID: 28487380.
  • Poole LG, Massey VL, Siow DL, Torres-González E, Warner NL, Luyendyk JP, Ritzenthaler JD, Roman J, Arteel GE. Plasminogen Activator Inhibitor-1 is Critical in Alcohol-enhanced Acute Lung Injury in Mice. Am J Respir Cell Mol Biol. 2017 Apr 26. doi: 10.1165/rcmb.2016-0184OC. [Epub ahead of print] PubMed PMID: 28445073.
  • Tanenbaum LN, Tsiouris AJ, Johnson AN, Naidich TP, DeLano MC, Melhem ER, Quarterman P, Parameswaran SX, Shankaranarayanan A, Goyen M, Field AS. Synthetic MRI for Clinical Neuroimaging: Results of the Magnetic Resonance ImageCompilation (MAGiC) Prospective, Multicenter, Multireader Trial. AJNR Am J Neuroradiol. 2017 Apr 27. doi: 10.3174/ajnr.A5227. [Epub ahead of print] PubMed PMID: 28450439.
  • Zagorski JW, Maser TP, Liby KT, Rockwell CE. Nrf2-Dependent and -Independent Effects of tert-Butylhydroquinone, CDDO-Im, and H(2)O(2) in Human Jurkat T Cells  as Determined by CRISPR/Cas9 Gene Editing. J Pharmacol Exp Ther. 2017May;361(2):259-267. doi: 10.1124/jpet.116.238899. Epub 2017 Mar 9. PubMed PMID: 28280124; PubMed Central PMCID: PMC5399638.

MAY

  • Bryleva EY, Keaton SA, Grit J, Madaj Z, Sauro-Nagendra A, Smart L, Halstead S, Achtyes E, Brundin L. The acute-phase mediator serum amyloid A is associated with symptoms of depression and fatigue. Acta Psychiatr Scand. 2017 May;135(5):409-418. doi: 10.1111/acps.12730. Epub 2017 Apr 4. PubMed PMID: 28374419.
  • Bailey JM, Colón-Rodríguez A, Atchison WD. Evaluating a Gene-Environment Interaction in Amyotrophic Lateral Sclerosis: Methylmercury Exposure and Mutated SOD1. Curr Environ Health Rep. 2017 Apr 10. doi: 10.1007/s40572-017-0144-1. [Epub ahead of print] Review. PubMed PMID: 28397096.
  • Boyd SA, Sallach JB, Zhang Y, Crawford R, Li H, Johnston CT, Teppen BJ, Kaminski NE. Sequestration of TCDD by activated carbon eliminates bioavailability and the suppression of immune function in mice. Environ Toxicol Chem. 2017 Apr 1. doi: 10.1002/etc.3815. [Epub ahead of print] PubMed PMID: 28370362.
  • Yu-Wai-Man C, Spencer-Dene B, Lee RM, Hutchings K, Lisabeth EM, Treisman R, Bailly M, Larsen SD, Neubig RR, Khaw PT. Local delivery of novel MRTF/SRF inhibitors prevents scar tissue formation in a preclinical model of fibrosis. Sci Rep. 2017 Mar 31;7(1):518. doi: 10.1038/s41598-017-00212-w. PubMed PMID: 28364121.
  • Rovati GE, Capra V, Shaw VS, Malik RU, Sivaramakrishnan S, Neubig RR. The DRY  motif and the four corners of the cubic ternary complex model. Cell Signal. 2017  Mar 24;35:16-23. doi: 10.1016/j.cellsig.2017.03.020. [Epub ahead of print] Review. PubMed PMID: 28347873.
  • Janney CA, Masheb RM, Lutes LD, Holleman RG, Kim HM, Gillon LR, Damschroder LJ, Richardson CR. Mental health and behavioral weight loss: 24-month outcomes in Veterans. J Affect Disord. 2017 Jun;215:197-204. doi: 10.1016/j.jad.2017.03.003. Epub 2017 Mar 11. PubMed PMID: 28340446.
  • Tykocki NR, Boerman EM, Jackson WF. Smooth Muscle Ion Channels and Regulation of Vascular Tone in Resistance Arteries and Arterioles. Compr Physiol. 2017 Mar 16;7(2):485-581. doi: 10.1002/cphy.c160011. PubMed PMID: 28333380.
  • Wang Y, Cui L, Xu H, Liu S, Zhu F, Yan F, Shen S, Zhu M. TRPV1 agonism inhibits endothelial cell inflammation via activation of eNOS/NO pathway. Atherosclerosis. 2017 Mar 10;260:13-19. doi: 10.1016/j.atherosclerosis.2017.03.016. [Epub ahead of print] PubMed PMID: 28324760.
  • Brown JA, Bugescu R, Mayer T, Gata-Garcia A, Kurt G, Woodworth HL, Leinninger GM. Loss of Action via Neurotensin-Leptin Receptor Neurons Disrupts Leptin and Ghrelin-Mediated Control of Energy Balance. Endocrinology. 2017 Mar 10. doi: 10.1210/en.2017-00122. [Epub ahead of print] PubMed PMID: 28323938.
  • Hutchings KM, Lisabeth EM, Rajeswaran W, Wilson MW, Sorenson RJ, Campbell PL, Ruth JH, Amin A, Tsou PS, Leipprandt JR, Olson SR, Wen B, Zhao T, Sun D, Khanna D, Fox DA, Neubig RR, Larsen SD. Pharmacokinetic optimitzation of CCG-203971: Novel inhibitors of the Rho/MRTF/SRF transcriptional pathway as potential antifibrotic therapeutics for systemic scleroderma. Bioorg Med Chem Lett. 2017 Apr 15;27(8):1744-1749. doi: 10.1016/j.bmcl.2017.02.070. Epub 2017 Mar 10. PubMed PMID: 28285914; PubMed Central PMCID: PMC5395305.
  • Zagorski JW, Maser TP, Liby KT, Rockwell CE. Nrf2-Dependent and -Independent  Effects of tert-Butylhydroquinone, CDDO-Im, and H(2)O(2) in Human Jurkat T Cells as Determined by CRISPR/Cas9 Gene Editing. J Pharmacol Exp Ther. 2017 May;361(2):259-267. doi: 10.1124/jpet.116.238899. Epub 2017 Mar 9. PubMed PMID: 28280124.
  • Subramanian M, MohanKumar SM, Balasubramanian P, Northcott CA, Garver H, Fink GD, MohanKumar PS. Chronic exposure to low doses of estradiol-17ß increases blood pressure in young female rats: A possible role for central Endothelin-1. Sci Rep. 2017 Dec;7(1):139. doi: 10.1038/s41598-017-00213-9. Epub 2017 Mar 10. PubMed PMID: 28273940.
  • Leal AS, Williams CR, Royce DB, Pioli PA, Sporn MB, Liby KT. Bromodomain inhibitors, JQ1 and I-BET 762, as potential therapies for pancreatic cancer. Cancer Lett. 2017 May 28;394:76-87. doi: 10.1016/j.canlet.2017.02.021. Epub 2017  Feb 27. PubMed PMID: 28254412.
  • Copple IM, Dinkova-Kostova AT, Kensler TW, Liby KT, Wigley WC. NRF2 as an Emerging Therapeutic Target. Oxid Med Cell Longev. 2017;2017:8165458. doi: 10.1155/2017/8165458. Epub 2017 Jan 31. PubMed PMID: 28250892; PubMed Central PMCID: PMC5306997.
  • Spradling-Reeves KD, Shade RE, Haywood JR, Cox LA. Primate response to angiotensin infusion and high sodium intake differ by sodium lithium countertransport phenotype. J Am Soc Hypertens. 2017 Feb 3. pii: S1933-1711(17)30035-9. doi: 10.1016/j.jash.2017.01.010. [Epub ahead of print] PubMed PMID: 28238630.
  • Ayala-Lopez N, Thompson JM, Watts SW. Perivascular Adipose Tissue's Impact on Norepinephrine-Induced Contraction of Mesenteric Resistance Arteries. Front Physiol. 2017 Feb 8;8:37. doi: 10.3389/fphys.2017.00037. eCollection 2017. PubMed PMID: 28228728; PubMed Central PMCID: PMC5296360.
  • Galligan JJ, Sternini C. Insights into the Role of Opioid Receptors in the GI Tract: Experimental Evidence and Therapeutic Relevance. Handb Exp Pharmacol. 2017;239:363-378. doi: 10.1007/164_2016_116. PubMed PMID: 28204957.
  • Kaska S, Brunk R, Bali V, Kechner M, Mazei-Robison MS. Deletion of Rictor in catecholaminergic neurons alters locomotor activity and ingestive behavior. Neuropharmacology. 2017 May 1;117:158-170. doi: 10.1016/j.neuropharm.2017.02.001. Epub 2017 Feb 3. PubMed PMID: 28167137; PubMed Central PMCID: PMC5386799.
  • Pandey M, Zhang JH, Mishra SK, Adikaram PR, Harris B, Kahler JF, Loshakov A,  Sholevar R, Genis A, Kittock C, Kabat J, Ganesan S, Neubig RR, Hoon MA, Simonds WF. A central role for R7bp in the regulation of itch sensation. Pain. 2017 May; 158(5):931-944. doi: 10.1097/j.pain.0000000000000860. PubMed PMID: 28134655;  PubMed Central PMCID: PMC5393936.
  • Ray JL, Kopec AK, Joshi N, Cline-Fedewa H, Lash LH, Williams KJ, Leung PS, Gershwin ME, Luyendyk JP. Trichloroethylene Exposure Reduces Liver Injury in a Mouse Model of Primary Biliary Cholangitis. Toxicol Sci. 2017 Apr 1;156(2):428-437. doi: 10.1093/toxsci/kfw264. PubMed PMID: 28115651.
  • Roth RA, Maiuri AR, Ganey PE. Idiosyncratic Drug-Induced Liver Injury: Is Drug-Cytokine Interaction the Linchpin? J Pharmacol Exp Ther. 2017 Feb;360(2):461-470. doi: 10.1124/jpet.116.237578. Epub 2016 Nov 15. PubMed PMID:  28104833.
  • Sjögren B. The evolution of regulators of G protein signalling proteins as drug targets - 20 years in the making: IUPHAR Review 21. Br J Pharmacol. 2017 Mar;174(6):427-437. doi: 10.1111/bph.13716. Epub 2017 Feb 8. Review. PubMed PMID: 28098342; PubMed Central PMCID: PMC5323514.
  • Joshi N, Kopec AK, Cline-Fedewa H, Luyendyk JP. Lymphocytes contribute to biliary injury and fibrosis in experimental xenobiotic-induced cholestasis.Toxicology. 2017 Feb 15;377:73-80. doi: 10.1016/j.tox.2016.12.009. Epub 2016 Dec 31. PubMed PMID: 28049044; PubMed Central PMCID: PMC5338728.
  • Li J, Phadnis-Moghe AS, Crawford RB, Kaminski NE. Aryl hydrocarbon receptor activation by 2,3,7,8-tetrachlorodibenzo-p-dioxin impairs human B lymphopoiesis.  Toxicology. 2017 Mar 1;378:17-24. doi: 10.1016/j.tox.2016.12.010. Epub 2016 Dec 31. PubMed PMID: 28049042; PubMed Central PMCID: PMC5293665.
  • Colón-Rodríguez A, Hannon HE, Atchison WD. Effects of methylmercury on spinal cord afferents and efferents-A review. Neurotoxicology. 2016 Dec 29. pii: S0161-813X(16)30259-5. doi: 10.1016/j.neuro.2016.12.007. [Epub ahead of print] PubMed PMID: 28041893.
  • Galligan JJ. 5-HT secretion by enterochromaffin cells is a very touching story. J Physiol. 2017 Jan 1;595(1):3. doi: 10.1113/JP273041. PubMed PMID: 28035678; PubMed Central PMCID: PMC5199740.=
  • Rorabaugh BR, Chakravarti B, Mabe NW, Seeley SL, Bui AD, Yang J, Watts SW, Neubig RR, Fisher RA. Regulator of G Protein Signaling 6 Protects the Heart from Ischemic Injury. J Pharmacol Exp Ther. 2017 Mar;360(3):409-416. doi: 10.1124/jpet.116.238345. Epub 2016 Dec 29. PubMed PMID: 28035008; PubMed Central PMCID: PMC5325075.
  • Rodriguez-Tapia ES, Naidoo V, DeVries M, Perez-Medina A, Galligan JJ. R-Type  Ca(2+) channels couple to inhibitory neurotransmission to the longitudinal muscle in the guinea-pig ileum. Exp Physiol. 2017 Mar 1;102(3):299-313. doi: 10.1113/EP086027. Epub 2017 Jan 25. PubMed PMID: 28008669; PubMed Central PMCID:  PMC5332280.
  • Kopec AK, Joshi N, Cline-Fedewa H, Wojcicki AV, Ray JL, Sullivan BP, Froehlich JE, Johnson BF, Flick MJ, Luyendyk JP. Fibrin(ogen) drives repair after acetaminophen-induced liver injury via leukocyte α(M)β(2) integrin-dependent upregulation of Mmp12. J Hepatol. 2017 Apr;66(4):787-797. doi: 10.1016/j.jhep.2016.12.004. Epub 2016 Dec 10. PubMed PMID: 27965156; PubMed Central PMCID: PMC5362307.
  • Rockwell CE, Turley AE, Cheng X, Fields PE, Klaassen CD. Persistent alterations in immune cell populations and function from a single dose of perfluorononanoic acid (PFNA) in C57Bl/6 mice. Food Chem Toxicol. 2017 Feb;100:24-33. doi: 10.1016/j.fct.2016.12.004. Epub 2016 Dec 8. PubMed PMID: 27939831.
  • Ismail A, Ayala-Lopez N, Ahmad M, Watts SW. 3T3-L1 cells and perivascular adipocytes are not equivalent in amine transporter expression. FEBS Lett. 2017 Jan;591(1):137-144. doi: 10.1002/1873-3468.12513. Epub 2016 Dec 21. PubMed PMID:  27926779; PubMed Central PMCID: PMC5235965.
  • Kovalova N, Nault R, Crawford R, Zacharewski TR, Kaminski NE. Comparative analysis of TCDD-induced AhR-mediated gene expression in human, mouse and rat primary B cells. Toxicol Appl Pharmacol. 2017 Feb 1;316:95-106. doi: 10.1016/j.taap.2016.11.009. Epub 2016 Nov 30. PubMed PMID: 27913140; PubMed Central PMCID: PMC5292778.
  • Hauser RA, Li R, Pérez A, Ren X, Weintraub D, Elm J, Goudreau JL, Morgan JC, Fang JY, Aminoff MJ, Christine CW, Dhall R, Umeh CC, Boyd JT, Stover N, Leehey M, Zweig RM, Nicholas AP, Bodis-Wollner I, Willis A, Kieburtz K, Tilley BC; NINDS NET-PD Investigators.. Longer Duration of MAO-B Inhibitor Exposure is Associated  with Less Clinical Decline in Parkinson's Disease: An Analysis of NET-PD LS1. J Parkinsons Dis. 2017;7(1):117-127. doi: 10.3233/JPD-160965. PubMed PMID: 27911341.
  • Ferland DJ, Darios ES, Neubig RR, Sjögren B, Truong N, Torres R, Dexheimer TS, Thompson JM, Watts SW. Chemerin-induced arterial contraction is G(i)- and calcium-dependent. Vascul Pharmacol. 2017 Jan;88:30-41. doi: 10.1016/j.vph.2016.11.009. Epub 2016 Nov 24. PubMed PMID: 27890480; PubMed Central PMCID: PMC5235970.
  • Haak AJ, Appleton KM, Lisabeth EM, Misek SA, Ji Y, Wade SM, Bell JL, Rockwell CE, Airik M, Krook MA, Larsen SD, Verhaegen M, Lawlor ER, Neubig RR. Pharmacological Inhibition of Myocardin-related Transcription Factor Pathway Blocks Lung Metastases of RhoC Overexpressing Melanoma. Mol Cancer Ther. 2017 Jan;16(1):193-204. doi: 10.1158/1535-7163.MCT-16-0482. Epub 2016 Nov 11. PubMed PMID: 27837031.
  • González-Reymúndez A, de Los Campos G, Gutiérrez L, Lunt SY, Vazquez AI. Prediction of years of life after diagnosis of breast cancer using omics and omic-by-treatment interactions. Eur J Hum Genet. 2017 Mar 8. doi: 10.1038/ejhg.2017.12. [Epub ahead of print] PubMed PMID: 28272536.Lutes LD, Damschroder LJ, Masheb R, Kim HM.

    APRIL
  • Gillon L, Holleman RG, Goodrich DE, Lowery JC, Janney C, Kirsh S, Richardson CR. Behavioral Treatment for Veterans with Obesity: 24-Month Weight Outcomes from the ASPIRE-VA Small Changes Randomized Trial. J Gen Intern Med. 2017 Mar 7. doi: 10.1007/s11606-017-3987-0. [Epub ahead of print] PubMed PMID: 28271430.Dunn AR,
  • Stout KA, Ozawa M, Lohr KM, Hoffman CA, Bernstein AI, Li Y, Wang M, Sgobio C, Sastry N, Cai H, Caudle WM, Miller GW. Synaptic vesicle glycoprotein 2C (SV2C) modulates dopamine release and is disrupted in Parkinson disease. Proc Natl Acad Sci U S A. 2017 Mar 14;114(11): E2253-E2262. doi:10.1073/pnas.1616892114. PubMed PMID: 28246328.
  • Parra-Cardona JR, Yeh HH, Anthony JC. Epidemiological research on parent-child conflict in the United States: subgroup variations by place of birth and ethnicity, 2002-2013. PeerJ. 2017 Jan 24;5: e2905. doi: 10.7717/peerj.2905. PubMed PMID: 28149684; PubMed Central PMCID: PMC5267568.
  • Brincks AM, Enders CK, Llabre MM, Bulotsky-Shearer RJ, Prado G, Feaster DJ. Centering Predictor Variables in Three-Level Contextual Models. Multivariate Behav Res. 2016 Dec 7:0. [Epub ahead of print] PubMed PMID: 27925836.
  • Cheng HG, Anthony JC. A new era for drinking? Epidemiological evidence on adolescent male-female differences in drinking incidence in the United States and Europe. Soc Psychiatry Psychiatr Epidemiol. 2017 Jan;52(1):117-126. doi: 10.1007/s00127-016-1318-0. PubMed PMID: 27915406; PubMed Central PMCID: PMC5233577.
  • Vsevolozhskaya OA, Anthony JC. Inter-relationships Linking Probability of Becoming a Case of Nicotine Dependence With Frequency of Tobacco Cigarette Smoking. Nicotine Tob Res. 2016 Dec;18(12):2278-2282. PubMed PMID: 27613940; PubMed Central PMCID: PMC5103934.
  • Kozlowski AJ, Fabian M, Lad D, Delgado A. Feasibility and safety of a powered exoskeleton for assisted walking for persons with multiple sclerosis: a single-group preliminary study. Arch Phys Med Rehabil. 2017 Mar 15. pii: S0003-9993(17)30144-2. doi: 10.1016/j.apmr.2017.02.010. [Epub ahead of print] PubMed PMID: 28315666.

    MARCH

  • Amin-Hanjani, S., Turan, T. N., Du, X., Pandey, D. K., Rose-Finnell, L., Richardson, D. et al. (2017). Higher Stroke Risk with Lower Blood Pressure in Hemodynamic Vertebrobasilar Disease: Analysis from the VERiTAS Study. J.Stroke Cerebrovasc.Dis., 26(2), 403-410. doi:S1052-3057(16)30375-5 [pii];10.1016/j.jstrokecerebrovasdis.2016.09.044 [doi]. Retrieved from PM:28029608
  • Bauer, M., Glenn, T., Monteith, S., Bauer, R., Whybrow, P. C., & Geddes, J. (2017). Ethical perspectives on recommending digital technology for patients with mental illness. Int.J.Bipolar.Disord., 5(1), 6. doi:10.1186/s40345-017-0073-9 [doi];10.1186/s40345-017-0073-9 [pii]. Retrieved from PM:28155206
  • Brincks, A. M., Enders, C. K., Llabre, M. M., Bulotsky-Shearer, R. J., Prado, G., & Feaster, D. J. (2016). Centering Predictor Variables in Three-Level Contextual Models. Multivariate.Behav.Res., 0. doi:10.1080/00273171.2016.1256753 [doi]. Retrieved from PM:27925836
  • Cheng, H. G., & Anthony, J. C. (2017). A new era for drinking? Epidemiological evidence on adolescent male-female differences in drinking incidence in the United States and Europe. Soc.Psychiatry Psychiatr.Epidemiol., 52(1), 117-126. doi:10.1007/s00127-016-1318-0 [doi];10.1007/s00127-016-1318-0 [pii]. Retrieved from PM:27915406
  • Cliburn, R. A., Dunn, A. R., Stout, K. A., Hoffman, C. A., Lohr, K. M., Bernstein, A. I. et al. (2016). Immunochemical localization of vesicular monoamine transporter 2 (VMAT2) in mouse brain. J.Chem.Neuroanat.. doi:S0891-0618(16)30095-3 [pii];10.1016/j.jchemneu.2016.11.003 [doi]. Retrieved from PM:27836486
  • Coles, A., Haveman-Gould, B., Farooq, M. U., Selke, K. J., & Gorelick, P. B. (2016). A Case of Complex PFO Leading to Ischemic Stroke: A Practical Clinical Pearl for Neurohospitalists. Neurohospitalist., 6(3), 114-117. doi:10.1177/1941874415588750 [doi];10.1177_1941874415588750 [pii]. Retrieved from PM:27366295
  • Combs, B., Hamel, C., & Kanaan, N. M. (2016). Pathological conformations involving the amino terminus of tau occur early in Alzheimer's disease and are differentially detected by monoclonal antibodies. Neurobiol.Dis., 94, 18-31. doi:S0969-9961(16)30119-X [pii];10.1016/j.nbd.2016.05.016 [doi]. Retrieved from PM:27260838


    FEBRUARY

  • Counts, S. E., Ikonomovic, M. D., Mercado, N., Vega, I. E., & Mufson, E. J. (2017). Biomarkers for the Early Detection and Progression of Alzheimer's Disease. Neurotherapeutics., 14(1), 35-53. doi:10.1007/s13311-016-0481-z [doi];10.1007/s13311-016-0481-z [pii]. Retrieved from PM:27738903
  • Cox, K., Combs, B., Abdelmesih, B., Morfini, G., Brady, S. T., & Kanaan, N. M. (2016). Analysis of isoform-specific tau aggregates suggests a common toxic mechanism involving similar pathological conformations and axonal transport inhibition. Neurobiol.Aging, 47, 113-126. doi:S0197-4580(16)30152-X [pii];10.1016/j.neurobiolaging.2016.07.015 [doi]. Retrieved from PM:27574109
  • Farooq, M. U., & Gorelick, P. B. (2016). Neurology Case Studies: Cerebrovascular Disease. Neurol.Clin., 34(3), 467-482. doi:S0733-8619(16)30001-9 [pii];10.1016/j.ncl.2016.04.001 [doi]. Retrieved from PM:27445238
  • Farooq, M. U., Goshgarian, C., Min, J., & Gorelick, P. B. (2016). Pathophysiology and management of reperfusion injury and hyperperfusion syndrome after carotid endarterectomy and carotid artery stenting. Exp.Transl.Stroke Med., 8(1), 7. doi:10.1186/s13231-016-0021-2 [doi];21 [pii]. Retrieved from PM:27602202
  • Fischer, D. L., Gombash, S. E., Kemp, C. J., Manfredsson, F. P., Polinski, N. K., Duffy, M. F. et al. (2016). Viral Vector-Based Modeling of Neurodegenerative Disorders: Parkinson's Disease. Methods Mol.Biol., 1382, 367-382. doi:10.1007/978-1-4939-3271-9_26 [doi]. Retrieved from PM:26611600
  • Ghosh, A., Tyson, T., George, S., Hildebrandt, E. N., Steiner, J. A., Madaj, Z. et al. (2016). Mitochondrial pyruvate carrier regulates autophagy, inflammation, and neurodegeneration in experimental models of Parkinson's disease. Sci.Transl.Med., 8(368), 368ra174. doi:8/368/368ra174 [pii];10.1126/scitranslmed.aag2210 [doi]. Retrieved from PM:27928028
  • Gorelick, P. B., & Farooq, M. U. (2016). Cerebral Microbleeds, Cognition, and Therapeutic Implications. JAMA Neurol., 73(8), 908-910. doi:2526489 [pii];10.1001/jamaneurol.2016.1388 [doi]. Retrieved from PM:27271086
  • Grabinski, T., & Kanaan, N. M. (2016). Novel Non-phosphorylated Serine 9/21 GSK3beta/alpha Antibodies: Expanding the Tools for Studying GSK3 Regulation. Front Mol.Neurosci., 9, 123. doi:10.3389/fnmol.2016.00123 [doi]. Retrieved from PM:27909397
  • Hamano, T., Shirafuji, N., Makino, C., Yen, S. H., Kanaan, N. M., Ueno, A. et al. (2016). Pioglitazone prevents tau oligomerization. Biochem.Biophys.Res.Commun., 478(3), 1035-1042. doi:S0006-291X(16)31271-2 [pii];10.1016/j.bbrc.2016.08.016 [doi]. Retrieved from PM:27543203
  • Harlow, M. L., Maloney, N., Roland, J., Guillen Navarro, M. J., Easton, M. K., Kitchen-Goosen, S. M. et al. (2016). Lurbinectedin Inactivates the Ewing Sarcoma Oncoprotein EWS-FLI1 by Redistributing It within the Nucleus. Cancer Res., 76(22), 6657-6668. doi:0008-5472.CAN-16-0568 [pii];10.1158/0008-5472.CAN-16-0568 [doi]. Retrieved from PM:27697767
  • Iadecola, C., Yaffe, K., Biller, J., Bratzke, L. C., Faraci, F. M., Gorelick, P. B. et al. (2016). Impact of Hypertension on Cognitive Function: A Scientific Statement From the American Heart Association. Hypertension, 68(6), e67-e94. doi:HYP.0000000000000053 [pii];10.1161/HYP.0000000000000053 [doi]. Retrieved from PM:27977393
  • Imamura, K., Sahara, N., Kanaan, N. M., Tsukita, K., Kondo, T., Kutoku, Y. et al. (2016). Calcium dysregulation contributes to neurodegeneration in FTLD patient iPSC-derived neurons. Sci.Rep., 6, 34904. doi:srep34904 [pii];10.1038/srep34904 [doi]. Retrieved from PM:27721502
  • Iqbal, K., Tran, D. A., Li, A. X., Warden, C., Bai, A. Y., Singh, P. et al. (2016). High type I error and misrepresentations in search for transgenerational epigenetic inheritance: response to Guerrero-Bosagna. Genome Biol., 17(1), 154. doi:10.1186/s13059-016-0981-5 [doi];10.1186/s13059-016-0981-5 [pii]. Retrieved from PM:27411809
  • Kang, S. S., Zhang, Z., Liu, X., Manfredsson, F. P., He, L., Iuvone, P. M. et al. (2017). alpha-Synuclein binds and sequesters PIKE-L into Lewy bodies, triggering dopaminergic cell death via AMPK hyperactivation. Proc.Natl.Acad.Sci.U.S.A, 114(5), 1183-1188. doi:1618627114 [pii];10.1073/pnas.1618627114 [doi]. Retrieved from PM:28096359
  • Kelly, S. C., He, B., Perez, S. E., Ginsberg, S. D., Mufson, E. J., & Counts, S. E. (2017). Locus coeruleus cellular and molecular pathology during the progression of Alzheimer's disease. Acta Neuropathol.Commun., 5(1), 8. doi:10.1186/s40478-017-0411-2 [doi];10.1186/s40478-017-0411-2 [pii]. Retrieved from PM:28109312
  • Korczyn, A. D., & Gorelick, P. B. (2016). In Memoriam: Milton Alter, MD, PhD (1929-2016). JAMA Neurol., 73(12), 1504. doi:2592268 [pii];10.1001/jamaneurol.2016.4562 [doi]. Retrieved from PM:27942731
  • Koss, D. J., Jones, G., Cranston, A., Gardner, H., Kanaan, N. M., & Platt, B. (2016). Soluble pre-fibrillar tau and beta-amyloid species emerge in early human Alzheimer's disease and track disease progression and cognitive decline. Acta Neuropathol., 132(6), 875-895. doi:10.1007/s00401-016-1632-3 [doi];10.1007/s00401-016-1632-3 [pii]. Retrieved from PM:27770234
  • Lee, S. H., Kim, B. J., Han, M. K., Park, T. H., Lee, K. B., Lee, B. C. et al. (2016). Should we exclude acute stroke patients with previous intracerebral hemorrhage from receiving intravenous thrombolysis? Int.J.Stroke, 11(7), 783-790. doi:1747493016654289 [pii];10.1177/1747493016654289 [doi]. Retrieved from PM:27312681
  • Lees, K. R., & Khatri, P. (2016). Stroke Treatment Academic Industry Roundtable Recommendations for Individual Data Pooling Analyses in Stroke. Stroke, 47(8), 2154-2159. doi:STROKEAHA.116.012966 [pii];10.1161/STROKEAHA.116.012966 [doi]. Retrieved from PM:27406108
  • Linklater, E. S., Tovar, E. A., Essenburg, C. J., Turner, L., Madaj, Z., Winn, M. E. et al. (2016). Targeting MET and EGFR crosstalk signaling in triple-negative breast cancers. Oncotarget., 7(43), 69903-69915. doi:12065 [pii];10.18632/oncotarget.12065 [doi]. Retrieved from PM:27655711
  • Lohr, K. M., Chen, M., Hoffman, C. A., McDaniel, M. J., Stout, K. A., Dunn, A. R. et al. (2016). Vesicular Monoamine Transporter 2 (VMAT2) Level Regulates MPTP Vulnerability and Clearance of Excess Dopamine in Mouse Striatal Terminals. Toxicol.Sci., 153(1), 79-88. doi:kfw106 [pii];10.1093/toxsci/kfw106 [doi]. Retrieved from PM:27287315
  • Machiela, E., Dues, D. J., Senchuk, M. M., & Van Raamsdonk, J. M. (2016). Oxidative stress is increased in C. elegans models of Huntington's disease but does not contribute to polyglutamine toxicity phenotypes. Neurobiol.Dis., 96, 1-11. doi:S0969-9961(16)30202-9 [pii];10.1016/j.nbd.2016.08.008 [doi]. Retrieved from PM:27544481
  • Mercado, N. M., Collier, T. J., Freeman, T., & Steece-Collier, K. (2016). Repairing the Aged Parkinsonian Striatum: Lessons from the Lab and Clinic. J.Clin.Cell Immunol., 7(6). doi:10.4172/2155-9899.1000476 [doi]. Retrieved from PM:28111608
  • Mufson, E. J., Ikonomovic, M. D., Counts, S. E., Perez, S. E., Malek-Ahmadi, M., Scheff, S. W. et al. (2016). Molecular and cellular pathophysiology of preclinical Alzheimer's disease. Behav.Brain Res., 311, 54-69. doi:S0166-4328(16)30305-9 [pii];10.1016/j.bbr.2016.05.030 [doi]. Retrieved from PM:27185734
  • Mufson, E. J., Perez, S. E., Nadeem, M., Mahady, L., Kanaan, N. M., Abrahamson, E. E. et al. (2016). Progression of tau pathology within cholinergic nucleus basalis neurons in chronic traumatic encephalopathy: A chronic effects of neurotrauma consortium study. Brain Inj., 30(12), 1399-1413. doi:10.1080/02699052.2016.1219058 [doi]. Retrieved from PM:27834536
  • Osgood, C. L., Maloney, N., Kidd, C. G., Kitchen-Goosen, S., Segars, L., Gebregiorgis, M. et al. (2016). Identification of Mithramycin Analogues with Improved Targeting of the EWS-FLI1 Transcription Factor. Clin.Cancer Res., 22(16), 4105-4118. doi:1078-0432.CCR-15-2624 [pii];10.1158/1078-0432.CCR-15-2624 [doi]. Retrieved from PM:26979396
  • Parra-Cardona, J. R., Yeh, H. H., & Anthony, J. C. (2017). Epidemiological research on parent-child conflict in the United States: subgroup variations by place of birth and ethnicity, 2002-2013. PeerJ., 5 , e2905. doi:10.7717/peerj.2905 [doi];2905 [pii]. Retrieved from PM:28149684
  • Polinski, N. K., Manfredsson, F. P., Benskey, M. J., Fischer, D. L., Kemp, C. J., Steece-Collier, K. et al. (2016). Impact of age and vector construct on striatal and nigral transgene expression. Mol.Ther.Methods Clin.Dev., 3, 16082. doi:10.1038/mtm.2016.82 [doi]. Retrieved from PM:27933309
  • Smith, E. E., Saposnik, G., Biessels, G. J., Doubal, F. N., Fornage, M., Gorelick, P. B. et al. (2017). Prevention of Stroke in Patients With Silent Cerebrovascular Disease: A Scientific Statement for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke, 48(2), e44-e71. doi:STR.0000000000000116 [pii];10.1161/STR.0000000000000116 [doi]. Retrieved from PM:27980126
  • Tiernan, C. T., Combs, B., Cox, K., Morfini, G., Brady, S. T., Counts, S. E. et al. (2016). Pseudophosphorylation of tau at S422 enhances SDS-stable dimer formation and impairs both anterograde and retrograde fast axonal transport. Exp.Neurol., 283(Pt A), 318-329. doi:S0014-4886(16)30195-9 [pii];10.1016/j.expneurol.2016.06.030 [doi]. Retrieved from PM:27373205
  • Van Raamsdonk, J. M., Vega, I. E., & Brundin, P. (2017). Oxidative stress in neurodegenerative disease: causation or association? Oncotarget.. doi:14650 [pii];10.18632/oncotarget.14650 [doi]. Retrieved from PM:28099897
  • Vega, I. E., & Collier, T. J. (2016). Editorial: Unraveling Neuroprotective and Neurodegenerative Signals in Neurodegeneration. Front Neurosci., 10, 328. doi:10.3389/fnins.2016.00328 [doi]. Retrieved from PM:27468259
  • Vsevolozhskaya, O. A., & Anthony, J. C. (2016). Inter-relationships Linking Probability of Becoming a Case of Nicotine Dependence With Frequency of Tobacco Cigarette Smoking. Nicotine.Tob.Res., 18(12), 2278-2282. doi:ntw159 [pii];10.1093/ntr/ntw159 [doi]. Retrieved from PM:27613940